Avidin Targeting of Intraperitoneal Tumor Xenografts
نویسندگان
چکیده
منابع مشابه
Avidin targeting of intraperitoneal tumor xenografts.
BACKGROUND Lectins (proteins that bind specific sugar molecules on glycoproteins and glycolipids) are expressed at various levels on the surface of tumor cells. Conjugation of cytotoxic agents to glycoproteins recognized by lectins could be useful in the treatment of tumors. Avidin (a highly glycosylated, positively charged protein found in egg white) contains terminal N-acetylglucosamine and m...
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ژورنال
عنوان ژورنال: JNCI: Journal of the National Cancer Institute
سال: 1998
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/90.1.25